Presentations by Centre Members

C4.4A as a prognostic marker in cancer.
Benedikte Jacobsen, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Structural mechanism of plasminogen activator inhibitor-1 target specificity.
Zhonghui Lin, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Structure of a protease-inhibitor complex: matriptase-sunflower trypsin inhibitor-1 complex.
Jacky Ngo, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Collagen turnover in cancer.
Niels Behrendt, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Antibodies and RNA aptamers inhibiting zymogen activation: Effects on cancer cell invasion.
Kenneth A. Bøtkjær, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Selection of nucleic acid aptamers against proteases, their inhibitors, and receptors.
Daniel M. Dupont, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

An effective tumour-targeting photosensitizer for photodynamic therapy.
Zhuo Chen, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Cancer stem/progenitor cells in vasculogenesis and angiogenesis.
Quansheng Zhoum, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

PET imaging of urokinase-type plasminogen activator receptor-containing tumour tissue,
Morten Persson, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Molecular imaging for tailored cancer therapy.
Andreas Kjær, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

NMR studies of proteins: From liquid- to solid-state NMR.
Niels Christian Nielsen, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Conformational forms of a peptidylic serine protease inhibitor.
Anna Sigrid Pii Svane, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Chemical synthesis of arginine analogous for protease inhibitors.
Masood Hosseini, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Peptide design for biopharmaceutical applications.
Knud Jensen, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

The urokinase-type plasminogen activator receptor and tumor plasticity.
Lin Yang, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Modulating the efficacy of urokinase-type plasminogen activator receptor-dependent formation of lamellipodia in cell culture.
Henrik Gårdsvoll, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

uPAR and plasma contact system in efferocytosis and procoagulation of 
apoptotic tumor cells.
Yi Wu, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Small molecule protease inhibitors.
Mingdong Huang, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Structure-function studies of a protease receptor.
Michael Ploug, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Type II transmembrane serine proteases in cancer.
Qingyu Wu, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Proteases in cancer: Prognostic factors and therapeutic targets.
Peter Andreasen, talk at Seventh scientific meeting of the Danish-Chinese centre for proteases and cancer, Suzhou, China.

Proteases and cancer.
Peter A. Andreasen, invited talk at College of Life Sciences, Peking University

RNA patamers and antibodies inhibting pro-uPA activation in vivo and in vitro.
Kenneth Bøtkjær, invited talk at the Department of Oncology, Cancer Research Centre UK, Cambridge Research Institute, UK.

Structure-function studies of uPARAP
Henrik Jessen Jürgensen, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.  

Chemical synthesis of arginine analogues and their incorporation in uPA-inhibiting peptides.
Masood Hosseini¸ talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

C4.4A binding peptides
Zhuo Liu, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

C4.4A expression in the normal mouse and initial attempts on constructing a targeting vector for a C4.4A knock out mouse
Mette Camilla Kriegbaum, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

PET imaging of uPAR expression in tumour xenografts  
Morten Persson, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

Modulating the efficacy of uPAR-dependent formation of lamellipodia in cell culture
Henrik Gårdsvoll, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

Conjugates between uPAR-binding peptides and iron nanoparticles                       
Line Hansen, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

Photo-dynamic therapy with Zn-phtalocyanin.
Zhuo Chen, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

Antibodies against uPARAP and MT1-MMP in animal tumour models.    
Maria C. Melander, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology, Aarhus University, Denmark.

RNA aptamers and antibodies inhibiting pro-uPA activation in vitro and in vivo.
Kenneth Bøtkjær, talk at Second Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Department of Molecular Biology Aarhus University, Denmark.

The urokinase receptor: From structure-function relationships to in vivo imaging.
Ploug, M., plenary speaker at 20th International Congress of The International Society for Fibrinolysis and Proteolysis, Amsterdam, The Netherlands.

PET Imaging of uPAR in human mice xenograft models.
Morten Persson, talk at the 2nd Copenhagen Graduate School of Health Sciences Annual Meeting, Denmark.

Structure, function and expression of C4.4A, a potential prognostic marker in non-small cell lung cancer.
Benedikte Jacobsen, invited talk at Laboratoire d'Organogénèse Expérimentale (LOEX), Québec, Canada.

Prognostic study of C4.4A in non-small cell lung cancer - Background and experimental set-up.
Benedikte Jacobsen, invited talk at Section of Translational Research, Thoraxklinik, Heidelberg, Germany.

Upain-1 - an ensemble story.
Anna Sigrid Pii Svane, talk at ”Dansk NMR møde”, Copenhagen, Denmark.

Rational design of new PET probes for non-invasive imaging of uPAR in preclinical cancer studies.
Michael Ploug
Invited talk at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.   

A new mechanism for matrix breakdown in tissue remodelling and cancer invasion: Interplay between collagen receptors and collagenolytic enzymes.
Niels Behrendt, invited talk at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.   

New principles for pharmacological interference with the plasminogen activation system.
Peter A. Andreasen
Invited talk at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.   

New Perspectives: Molecular imaging with pet and tailored therapy
Andreas Kjær, invited talk at Scandinavian Medical Technology Conference, Copenhagen.

Molecular imaging with pet for tailored radioation therapy radioation therapy
Andreas Kjær, invited talk at Acta Oncologica Symposium, Biology-Guided Adaptive Radiotherapy, Aarhus, Denmark, May 2010.

New Strategies in Pharmaceutical Research: Molecular Imaging with PET and Drug Development
Andreas Kjær, invited talk at University of Vienna, Pharmacology conference, Vienna, Austria.

Molecular Imaging with PET for Tailored Radioation Therapy
Andreas Kjær, invited talk at INKEP, Oxford University, Oxford, UK

Nanomedicine
Kjems, J.
Invited talk at Joint Danish-Chinese conference on Bio-medicine and Synthetic Biology, Hong Kong Science Park, China

The composite function of protelytic and endocytic processes in matrix turnover and cancer invasion
Behrendt, N.
Invited talk at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA

The urokinase receptor - from crystal structure to in vivo imaging
Ploug, M.
Invited talk at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA

The plasminogen activation system in bony fish
Andreasen, P.A.
Invited talk at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA

Serine proteases: Regulatory mechanisms and pharmacological intervention
Andreasen, P.A.
Lecture at the Faculty of Life Sciences, University of Copenhagen.

Tumour imaging
Kjær, A.
Lecture on Ph.D. course in Tumor Biology and Clinical Oncology at the Faculty of Health Sciences, University of Copenhagen

Imaging of the uPA receptor – an example of PET probe development
Ploug, M.
Lecture on Ph.D. course in Tumour Biology and Clinical Oncology at the Faculty of Health Sciences, University of Copenhagen

Matrix degradation in invasion – biochemical aspects
Behrendt, N.
Lecture on Ph.D.-course in Tumour Biology and Clinical Oncology at the Faculty of Health Sciences, University of Copenhagen

PET imaging of uPAR-containing tumour tissue
Persson, M.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Animal tumour models, uPARAP, MT1-MMP
Melander, M.C.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

New peptides binding to proteases and related proteins
Sørensen, H.P.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Functional and structural studies of serpins and LRP ligand-binding domains
Jensen, J.K.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

The C4.4A gene
Chen, Z.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

C4.4A as a prognostic marker
Jacobsen, B.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Structure-function relationships of uPAR
Gårdsvoll, H.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Antibodies and RNA aptamers inhibiting pro-uPA activation
Bøtkjær, K.A.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmar

Chemical synthesis of arginine analogues and their incorporation in uPA-inhibiting peptides
Hosseini, M.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Ensemble average solution structure of a uPA-inhibiting peptide, determined by NMR
Svane, S.P. and Nielsen, N.C.
Talk at First Annual Scientific Meeting for Danish Participants in Danish-Chinese Centre for Proteases and Cancer, Copenhagen Biocentre, Denmark

Harnessing siRNA by chemical modifications and polymeric nanocarrier systems for therapy
Kjems, J.
Invited talk at School of Stomatology, The Fourth Military Medical University, Xian, China

PAI-1 as a prognostic marker and a potential therapeutic target in oral carcinoma
Gao, S.
Invited talk at School of Stomatology, The Fourth Military Medical University, Xian, China

Toll-like receptor 4 in tumors
Liu, M.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

The C4.4A gene
Chen, Z.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Functional and structural studies of serpins and LRP ligand-binding domains
Jensen, J.K.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Structural studies of proteases and related proteins
Huang, M.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

RNA aptamers binding to PAI-1
Andreasen, P.A.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Inhibitors of metalloproteases
Sørensen, H.P.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Chemical synthesis of arginine analogues and their incorporation in mupain-1/upain-1
Hosseini, M.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Application of nucleic acid based therapeutics targeting PAI-1 in oral squamous cell carcinomas
Gao, S.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Synthetic bioorganic chemistry and nanobioscience
Jensen, K.J.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

RNA-based therapeutics
Kjems, J.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Introduction to proteases and cancer
Andreasen, P.A.
Talk at Denmark-China Joint Symposium on Proteases and Cancer, Wuyishan, China

Harnessing siRNA by chemical modifications and polymeric nanocarrier systems for therapy
Kjems, J.
Keynote talk at “Asia RNAi”, Kunshan, China

Application of siRNA in animal models
Kjems, J.
Invited talk at Chinese Continuing Educational Course on Oral Mucosal Diseases, Beijing

PAI-1 as a prognostic marker and a potential therapeutic target in oral carcinoma
Gao, S.
Invited talk at Chinese Continuing Educational Course on Oral Mucosal Diseases, Beijing, China

PAI-1 as a prognostic marker and a potential therapeutic target in oral carcinoma
Gao, S.
Invited talk at the Dental School, the Central South University, Changsha, China

Molecular imaging for tailored cancer therapy
Kjær, A.
Talk at opening seminar of the Danish-Chinese Centre for Proteases and Cancer, Aarhus University, Denmark

Structural studies of proteases
Huang, M.
Talk at opening seminar of the Danish-Chinese Centre for Proteases and Cancer, Aarhus University, Denmark

Danish-Chinese Centre for Proteases and Cancer
Andreasen, P.A.
Talk at opening seminar of the Danish-Chinese Centre for Proteases and Cancer, Aarhus University, Denmark

The composite functions of proteolytic and endocytic processes in matrix degradation and cancer invasion
Behrendt, N.
Talk at Scientific seminar in Danish-Chinese Centre for Proteases and Cancer at the Copenhagen Biocentre, Denmark

Structural studies of proteases and their receptors
Huang, M.
Talk at Scientific seminar in Danish-Chinese Centre for Proteases and Cancer at the Copenhagen Biocentre, Denmark

Protein interactions: Determination of binding characteristics by surface plasmon resonance
Andreasen, P.A.
Talk at Ph.D. course in Translational Medicine at the Medical Faculty, Aarhus University, Denmark

Molecular imaging with PET for tailored cancer therapy.
Kjær, A.
Invited talk at Shuguang Hospital, Shanghai, China.

The function of the endocytic receptor uPARAP/endo180 in collagen clearance
Behrendt, N., Madsen, D.H., Jürgensen, H.J., Hillig, T., Ingvarsen, S., Engelholm, L.H.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA

Protease nexin-1 as an inhibitor of plasminogen activation
Kousted, T.M, Andersen, L.M., Sochalska, M., Vitved, L., Danø, K., Koch, C., and Andreasen, P.A.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA.

Studies of ligand-induced morphological changes in cells over-expressing the urokinase receptor (uPAR)
Gårdsvoll, H., Jacobsen, B., Krigsbaum, M., Engelholm, L.H., Behrendt, N., and Ploug, M.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA

Urokinase-type plasminogen activator (uPA) in zebrafish
Bager, R., Kristensen, T.K., Szczur, A., Andersen, L.M., Christensen, A., and Andreasen, P.A.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA

Structural Basis for the species specifity of the uPA-uPAR interaction
Lin, L., Gårdsvoll, H., Huai, Q., Østergaard, S., Huang, M., Ploug, M.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA

Crystal structure of a soluble urokinase receptor mutant in its ligand-free form
Xu, X., Gårdsvoll, H., Ploug, M., ad Huang, M.
Talk at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA

Proteases in cancer, mechanisms and clinical implications
Andreasen, P.A.
Invited talk at a symposium on “Molecular oncology” at the inauguration of Department of Molecular Medicine at Skejby Sygehus, Aarhus, Denmark

Plasminogen activitor inhibitors and oral squamous cell carcinomas
Gao, S.
Invited talk at Capital Medical University School of Stomatology,   Beijing, China

C4.4.A as a prognostic marker
Ploug, M.
Invited talk at Capital Medical University School of Stomatology,   Beijing, China

Proteases and cancer
Andreasen, P.A.
Invited talk at Capital Medical University School of Stomatology,   Beijing, China

RNA-based therapeutics
Gao, S.
Invited talk at Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

C4.4.A as a prognostic marker
Ploug, M.
Invited talk at Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Proteases and cancer
Andreasen, P.A.
Invited talk at Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Solid state NMR
Nielsen, N.C.
Invited talk at State Key Laboratory of Magnetic Resonance, Chinese Academy of Sciences, Wuhan Institute of Physics and Mathematics, Wuhan, China

Plasminogen activitor inhibitors and oral squamous cell carcinomas
Gao, S.
Invited talk at Wuhan University School of Stomatology, Wuhan, China

Molecular embryology
Füchtbauer, E.-M.
Invited talk at Wuhan University School of Stomatology, Wuhan, China

Proteases and cancer
Andreasen, P.A.
Invited talk at Wuhan University School of Stomatology, Wuhan, China