PET imaging of proteolysis: Evaluation of 68Ga-DOTA and 68Ga-NODAGA chelates of an uPAR-specific peptide in a human glioblastoma xenograft model.
Persson, M., Madsen, J., Østergaard, S., Ploug, M., and Kjaer, A. (2011) Poster at 102nd American Association of Cancer Research Annual Meeting, Orlando, Florida, USA.
Synthesis of arginine analogs - investigating the P1 of urikinase-type plasminogen activator inhibitors upain-1 and mupain-1.
Hosseini, M., Andreasen, P.A., and Jensen, K.J. (2010) Poster presentation at the “31st European Peptide Symposium”, Copenhagen, Denmark.
Secondary structure modifications of serine protease inhibitor upain-1 to improve binding-affinity.
Roodbeen, R., Andreasen, P.A., and Jensen, K.J. (2010) Poster presentation at the “31st European Peptide Symposium”, Copenhagen, Denmark.
Structural stability is critical for inhibitory effect of a cyclic peptide.
Svane, A.S.P. (2010) Poster at EUROMAR/ISMAR, Firenze, Italy.
Optimized tagging of recombinant proteins produced in Drosophila S2 cells using the third domain of the urokinase receptor for efficient one-step purification.
Gårdsvoll, H. and Ploug, M. (2010) Poster at PEGS Europe 2nd Meeting, "Protein and Antibody Engineering Summit" Hannover, Germany.
NMR and MRI studies of protease inhibitors in relation to cancer.
Jensen, B.P. (2010) Poster at ”Dansk NMR møde”, Copenhagen, Denmark.
Synthesis of a 64Cu-labeled peptide and its application for non- invasive PET imaging of uPAR in cancer xenografts in mice.
Persson, M., Madsen, J., Østergaard, S., Ploug, M., and Kjaer, A. (2010) Poster at World Molecular Imaging Congress, Kyoto, Japan.
Non-invasive detection of urokinase-type plasminogen activator receptor (uPAR) expression in four human cancer xenograft mouse models using microPET/CT.
Persson, M., Madsen, J., Østergaard, S., Ploug, M., and Kjaer, A. (2010) Poster at the 101st American Association of Cancer Research Annual Meeting, Washington D.C., USA.
Monoclonal antibodies inhibiting active- and zymogen-form of urokinase-type plasminogen activator.
Fogh, S., Bøtkjær, K.A., Blouse, G.E., Deryugina, E.I., Quigley, J.P., and Andreasen, P.A. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Expression and metastasis-associated protein C4.4A in the wild-type mouse.
Kriegbaoum, M.C., Jacobsen, B., and Ploug, M. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Monolconal antibodies against human protease nexin-1.
Kousted, T.M., Lacroix, C., Andersen, L.M., Sochalska, M., Vitved, L., Danø, K., Koch, C., and Andreasen, P.A. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Detecting and interfering with the collagenolytic enzyme MT1-MMP.
Ingvarsen, S., Engelholm, L.H., Madsen, D.H., Jürgensen, H.J., Melander, M.C., Lund, L.D., Holmbeck, K., and Behrendt, N. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Structure-based engineering of species selectivity in the interaction between urokinase and its receptor: Implication for preclinical cancer therapy.
Lin, L., Gårdsvoll, H., Huai, Q., Huang, M., and Ploug, M. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Synthetic nucleic acids targeting PAI-1 as a potential therapeutic tool in oral squamous cell carcinomas.
Gao, S., Villedsen, S., Jensen, T.I., Bøtkjær, K.A., Dupont, D.M., Larsen, E.K.U., Andreasen, P.A., and Kjems, J. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
RNA aptamers to uPA and PAI-1 for studying the pathophysiological role of the uPA system.
Dupont, D.M., Madsen, J.B., Bøtkjær, K.A., Gao, S., Tavitian, B., Ducongé, F., Kjems, J., and Andreasen, P.A. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
The collagen receptor uPARAP/Endo180 is a functional biomarker for the phagocytic subpopulation of human gingival fibroblasts.
Fang, C., Su, Z., Fan, M., Jian, X., and Behrendt, N. (2010) Poster at the at the “Danish Cancer Symposium on “Cancer Invasion: Mechanisms and Therapeutic Options”, Copenhagen, Denmark.
Investigation of the role of uPARAP/Endo180 in a syngeneic osteosarcoma mouse model.
Melander, M.C. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
The calcium-binding lectin domain of the collagen receptor, uPARAP/Endo180, is active in modulating the binding to basement membrane collagen.
Jürgensen, H.J. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
Collagen degradation mediated by endocytic receptors.
Madsen, D. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
Urokinase-type plasminogen activator (uPA) in zebrafish.
Bager, R. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
RNA aptamers as conformational probes and regulatory agents for plasminogen activator inhibitor-1.
Jensen, J.K. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
Selective abrogration of uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation.
Connolly, B.M., Choi, E.Y., Gårdsvoll, H., Bey, A., Currie, B.M., Chavakis, T., Lui, S., Molinolo, A., Ploug, M., Leppla, S.H., Bugge, T.H. (2010) Poster at the Gordon Research Conference on Plasminogen Activation and Extracellular Proteolysis, Ventura, CA, USA.
A novel model of intervention with serine protease activity - tagrgeting zymogen activation.
Bøtkjar, K.A., Blouse, G.E., Deryugina, E.I., Kjelgaard, S., Byszyk, O., Mortensen, K.K., Quigley, J.P., Andreasen, P.A. (2009) Poster at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA.
Preliminary crystallographic study of human C4.4A, a structural uPAR homologue.
Lin, L., Gårdsvoll, H., Huai, Q., Østergaard, S., Huang, M., Ploug, M. (2009) Poster at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA.
B6-PLAUGFGDhu/GFDhu - A novel knock-in mouse strain for functional dissection of the uPA-uPAR interaction in vivo.
Connolly, B.M, Gårdsvoll, H., Choi, E.Y., Bey, A., Currie, B.M., Chavakis, T., Lui, S., Ploug, M., Leppla, S.H., Bugge, T.H. (2009) Poster at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA.
Crystal structures of a soluble receptor mutant in its ligand-free form and in complex with its ligand uPA.
Huang, M. (2009) Poster at the 2009 Workshop on Molecular and Cellular Biology of Plasminogen Activation, Cold Spring Harbor, NY, USA.
Expression of C4.4A in precursor lesion of non-small cell lung cancer.
Jacobsen, B., Santoni-Rugiu, E., Illemann, M., Lærum, O.D., Ploug, M. (2009) Poster at the 13th World Conference on Lung Cancer, San Francisco, CA, USA.
C4.4A is am early marker of squamous differentiation in non-small cell lung cancer.
Jacobsen, B., Santoni-Rugiu, E., Illemann, M., Lærum, OD., Ploug, M. (2009) Poster at Gordon Research Conference on Epithelial differentiation and Keratinization, Les Diablerets, Switzerland.
Synthesis and characterization of a 68Ga-labeled linear peptide for non-invasive detection of urokinase-type plasminogen activator receptor (uPAR) expression in human cancer.
Persson, M., Madsen, J., Ploug, M., Kjaer, A. (2009) World Molecular Imaging Congress, Montreal, Canada.
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